Monday, October 25, 2021

Manganese a promising new catalyst for drug synthesis - European Pharmaceutical Review

Last updated Wednesday, October 6, 2021 06:26 ET , Source: NewsService

Researchers have found that manganese can simplify the process of synthesising fluoroketones for drug design and manufacture.

A team of researchers at Rice University, US, have revealed that manganese salt simplifies the process of fluoroketones, precursor molecules for drug design and manufacture.

Previously, the complex method required expensive silver catalysts. A new study, published in ACS Catalysis, investigated how to replace this method with a cerium-based compound. That in turn led the researchers to eye manganese as a next-level catalyst.

Attaching negatively charged fluorine atoms to ketones helps direct the functional groups toward desired reactions when used in anti-cancer and other compounds, explained Rice chemist Julian West. West also noted in a previous study that replacing hydrogen atoms with fluorine “is like armour plating at that position” and helps drugs last longer in the body.


Leveraging extended reality (XR) technology to drive laboratory productivity

The key to creating and implementing a digital strategy is determining where efficiencies can be made and where technologies can provide a competitive edge. In this on-demand webinar, you will learn from Katie Evans , Senior Product Manager, Thermo Fisher Scientific, how SampleManager XR software and Microsoft HoloLens can support those efforts and drive forward digital transformation.

Some of the advantages of using manganese include its low cost and great availability. “The...

Read Full Story: https://www.europeanpharmaceuticalreview.com/news/163686/manganese-a-promising-new-catalyst-for-drug-synthesis/

Your content is great. However, if any of the content contained herein violates any rights of yours, including those of copyright, please contact us immediately by e-mail at media[@]kissrpr.com.