UK: Results from a prospective multimodality two-center observational study have shown that patients recovering from severe COVID-19 do not have evidence of left ventricular dysfunction compared with comorbidity-matched volunteers. However, right ventricular abnormalities do occur and likely indicate the consequences of severe viral pneumonia.
The study results, published in the BMJ journal Heart, suggest that prior reports of left ventricular myocardial abnormalities following COVID-19 may indicate pre-existing comorbidities.
There has been a major interest in the cardiac consequences of COVID-19, and it is requisite to establish the true impact of COVID-19 and its impact on healthcare in the years to follow. Trisha Singh, BHF Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, Edinburgh, UK, and colleagues, therefore, aimed to determine the contribution of comorbidities on the reported widespread myocardial abnormalities in patients with recent COVID-19.
For this purpose, patients hospitalized with confirmed COVID-19 underwent gadolinium and manganese-enhanced MRI and CT coronary angiography (CTCA). They were compared with healthy and comorbidity-matched volunteers after blinded analysis.
In 52 patients (median age: 54 years, 39 males) who recovered from COVID-19, one-third (n=15, 29%) were admitted to intensive care and a fifth (n=11, 21%) were ventilated.
Key findings of the study include:
- Twenty-three patients underwent CTCA, with one-third...
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