Global Hyperpigmentation Disorder Treatment Market Outlook 2031
- The global hyperpigmentation disorder treatment market was valued at US$ 4.3 Bn in 2021
- The global market is projected to advance at a CAGR of 8.5% from 2022 to 2031
- The global hyperpigmentation disorder treatment market is anticipated to reach more than US$ 9.5 Bn by the end of 2031
Hyperpigmentation Disorder Treatment Market Introduction
Pigmentation refers to areas of the skin that have darkened in color compared to the surrounding skin, often resulting in a patchy or uneven appearance. Pigmentation can appear as freckles and sunspots, melasma or chloasma, seborrheric keratosis, and birthmarks. It can be exacerbated by the usage of inappropriate skin care products as well as continued sun exposure and heat trauma. Hyperpigmentation occurs when melanocytes in the deeper layers of the skin produce melanin, a skin-darkening pigment.
Melanin overproduction can result in darker skin patches on the skin’s surface. Skin hypopigmentation is caused by a decrease in melanin production. Hyperpigmentation disorders can be treated with cosmeceuticals, laser treatment, and chemical peels. Furthermore, rise in prevalence of melasma and increase in awareness about hyperpigmentation treatment are driving the global hyperpigmentation disorders treatment market size.
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Hyperpigmentation is quite common and relatively harmless. It could be a source of embarrassment for those who suffer from it. Hyperpigmentation, or a dark pigmentation patch on the face, causes an abnormally high concentration of skin pigments responsible for the production of melanocytes. Hyperpigmentation is most common in Mediterranean, Asian, African, and Latino populations.
Advancements in Cosmeceutical Nanotechnology for Hyperpigmentation Treatment
Hyperpigmentation is a widespread and serious skin condition that affects people of all skin types. Despite the availability of various depigmentation active ingredients for skin hyperpigmentation disorders, none are completely satisfactory due to poor permeability through the skin layer and significant toxicity, resulting in severe side effects such as irritant dermatitis, erythema, itching, and skin flaking. Nanotechnology plays an important role in advancing cosmeceutical formulation by improving active ingredient solubility, stability, safety, loading efficiency, and dermal permeability.
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Scientists have been investigating how nanotechnology can improve active ingredient delivery and absorption to the skin in addition to focusing on improving the efficacy of individual active agents. Nanotechnology has become a promising addition to the cosmetic industry due to its ability to improve the properties of cosmetic products in general. Nanotechnology has the potential to manipulate and improve features such as absorption, texture, active ingredient protection, and overall efficiency.
Depigmentation active ingredients such as hydroquinone, arbutin, kojic acid, azelaic acid, and retinoic acid; and new approaches in nanotechnology could improve the efficacy of hyperpigmentation treatments. Nanotechnology is a promising approach for topical hydroquinone administration to overcome hyperpigmentation with adequate skin penetration and low systemic absorption to reduce hydroquinone’s adverse effects.
Increase in Substitution of Conventional Agents with Cosmeceuticals for Skin Care
In terms of treatment type, the cosmeceuticals segment held significant market share in 2021. Cosmeceuticals are topical cosmetic-pharmaceutical blends that contain biologically active ingredients. They can enhance skin appearance. Cosmeceuticals are rapidly substituting conventional agents. Phytochemicals, or compounds derived from plants, are cosmeceuticals that have been shown to have a range of cellular effects for a number of dermatological diseases. Furthermore, cosmeceuticals are regularly used to treat hyperpigmentation. Hyperpigmentation disorders are generally difficult to treat, which necessitates the usage of skin lightening agents such as cosmeceuticals. These target hyperplastic melanocytes and inhibit key regulatory steps in melanin synthesis. Cosmeceuticals are the commonly preferred treatment measures in facial hyperpigmentation disorders due to high absorption and penetration in the skin.
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Rise in Prevalence Driving Melasma Segment
Based on disease indication, the melasma segment accounted for the largest global hyperpigmentation disorder treatment market share in 2021. Melasma is a typically acquired condition of symmetric hyperpigmentation that usually affects the face. It is more common in women and people with darker skin types. Skin conditions such as melasma are quite prevalent, especially in pregnant women. Melasma affects 15% to 50% of pregnant mothers. Melasma can affect 1.5% to 33% of people, and it typically appears during a woman’s reproductive years and infrequently during puberty. It typically begins between the age of 20 and 40. Rise in prevalence of melasma and increase in preference for cosmeceutical treatment have led to high demand for dermatological care. Melasma was significantly widespread in 2020, affecting more than 5 million people in the U.S. Asian women of childbearing age have melasma prevalence of up to 30%. It frequently recurs and is challenging to treat. The pathogenesis, clinical staging & classification, and clinical management of melasma have advanced significantly in the past few years. As per global hyperpigmentation disorders treatment market trends, rise in prevalence of melasma and increase in treatment options are expected to drive the segment in the next few years.
Provision of Laser Treatment & Phototherapy to Fuel Esthetic Clinics & Dermatology Centers Segment
In terms of end-user, the esthetic clinics & dermatology centers segment is projected to account for major share of the global hyperpigmentation disorder treatment market during the forecast period. Increase in number of esthetic clinics & dermatological centers is expected to drive the segment in the near future. Manufacturers and retailers of hyperpigmentation cosmeceutical products are improving their supply chains to meet the growing demand for hyperpigmentation disorder treatment products. Other global players and retailers are encouraging several brands to adopt an omnichannel supply model for products to reach final customers.
Patients experience significant social and emotional stress due to hyperpigmentary disorders, particularly melasma and post-inflammatory hyperpigmentation (PIH). Despite the development of several treatment modalities for melasma and PIH, management of these conditions is difficult due to recurrent and refractory nature. Lasers have revolutionized the treatment of a number of dermatological conditions, particularly dermal or mixed melasma; pigmentary disorders are one of these. Lasers have been widely used to treat pigmented conditions such as Becker’s nevus, cafe-au-lait macules, Nevus of Ota, nevocellular nevi, lentigines, tattoos, melasma, and post-inflammatory hyperpigmentation, with varying degrees of success.
Regional Outlook of Global Hyperpigmentation Disorder Treatment Market
Asia Pacific accounted for the largest share of around 35% of the global hyperpigmentation disorder treatment market in 2021. The market in the region is projected to be highly lucrative during the forecast period. Rise in adoption of laser treatment for several skin diseases, decrease in social taboos & increase in acceptance of pigmentation disorders treatment measures, surge in prevalence of numerous skin disorders, rise in awareness about skin rejuvenation, improvement in lifestyle, and increase in disposable income are expected to drive the market in the region.
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Different geographic regions of the world, skin races, and age groups have different epidemiologies for pigmentary disorders. Around 6.9% of the patients in a Northern Indian study on childhood and adolescent dermatoses had pigmentary disorders. According to a study published in the International Journal of Molecular Sciences in 2018, dark-skinned people (South/Southeast Asian, Hispanic/Latin American, and African descent) have a higher prevalence of pigmentary disorders. These are also the third and fourth most common dermatoses in African Americans and Hispanics, respectively. Hence, the market in the region is expected to be driven by high prevalence of pigmentation disorders.
Analysis of Key Players in Global Hyperpigmentation Disorder Treatment Market
The global hyperpigmentation disorder treatment market is consolidated, with the presence of small number of leading players. Expansion of product portfolio and mergers & acquisitions are the key strategies adopted by the major players in the global hyperpigmentation disorder treatment market. Aerolase Corporation, Candela Corporation, Cynosure, Galderma S.A., iSCLINICAL, ISDIN, L’Oréal (SkinCeuticals, Skin betterscience & La Roche-Posay), LumenisBe Ltd., Mesoestetics, Obagi Cosmeceuticals LLC, PCA Skin, Scientis, Senté, and Skin Medica (AbbVie) are the prominent players operating in the global hyperpigmentation disorder treatment market and the hyperpigmentation treatment devices market.
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